Molecular multi-tools turn existing drug into RNA-targeting compound
Metastatic breast cancer and Alport syndrome respond to the new compounds, offering a strategy for broadly tackling untreatable diseases.read more
View ArticleDual-action breast cancer compounds overcome common drug-resistance issues
By distorting estrogen receptor shape in two different ways, compounds offer a two-for-one punch to estrogen-sensitive cancer cells.read more
View ArticleScripps Research Professor Chi-Huey Wong receives Robert A. Welch Award in...
LA JOLLA, CA— The Welch Foundation, one of the nation’s largest sources of private funding for basic chemical research, has announced that Scripps Research Professor Chi-Huey Wong, PhD , is the 2021...
View ArticleInfectious disease sleuth Sumit Chanda, PhD, joins Scripps Research and its...
LA JOLLA, CA— Leading infectious disease researcher Sumit Chanda, PhD, will join the Scripps Research Department of Immunology and Microbiology and its nonprofit drug discovery and development...
View ArticleScripps Research Fellows Program launches new recruiting season, seeking...
Igniting high-impact scientific careers is the goal of elite Scripps Research Fellows Program, now in its fifth year.read more
View ArticleFlu discovery points to target for antiviral drugs
Scientists discover a ploy used by multiple pathogens to thwart cellular defenses, offering a new strategy for antiviral development.read more
View ArticleResearchers use directed evolution technique to speed up protein production...
LA JOLLA, CA— Scientists at Scripps Research have used directed-evolution techniques to speed up the workings of protein-making factories in cells called ribosomes. The achievement is a basic...
View ArticleEarly detection of atrial fibrillation with a wearable patch may help reduce...
Study finds that wearing a heart rhythm-recording patch for early detection of AFib was associated with a lower rate of stroke, heart attack, or blood clots three years later.read more
View ArticleSan Diego research centers receive $15 million to train next generation of...
LA JOLLA, CA —Three San Diego research institutions have been awarded nearly $15 million from the California Institute of Regenerative Medicine (CIRM) to train the next generation of scientists in...
View ArticleNew research consortium to tackle maternal health disparities with digital...
Mobile app-based research platform aims to engage and empower researchers and participants across the country .read more
View ArticleCalibr announces preliminary clinical data from first-in-human clinical trial...
Two of the first three patients in the lowest dose cohort experienced a complete response to therapy with the longest response being 11 months (ongoing) at the time of data cut-off The novel switchable...
View ArticleClinical trial starts for prospective ALS treatment co-developed at Scripps...
LA JOLLA, CA— An experimental treatment called 3K3A-APC, which was co-developed at Scripps Research and has shown promise against amyotrophic lateral sclerosis (ALS) in preclinical studies, is now...
View ArticleScripps Research discovery illuminates how brain cells die in prion diseases
Researchers show how toxic aggregates are formed inside brain cells, and how to block the cell-killing process—which may also be at work in Alzheimer’s and other neurodegenerative diseases.read more
View ArticleNo more annual flu shot? Scripps Research and collaborators find new target...
A new antibody discovered in the blood of some people vaccinated against or infected with influenza can recognize a broad variety of flu viruses.read more
View ArticleCompound in the herb rosemary may be useful against COVID-19 and other...
LA JOLLA, CA— A team co-led by scientists at Scripps Research has found evidence that a compound contained in the medicinal and culinary herb rosemary could be a two-pronged weapon against the...
View ArticleScripps Research scientists unveil promising new approach to diabetes prevention
A Scripps Research team found a compound that protects against diabetes-like metabolic changes in obese mice, including the reduction in liver fat deposits of treated obese mice (right) compared to...
View ArticleNew role for cyanide in early Earth and search for extraterrestrial life
Scripps Research chemists discovered how cyanide could have enabled chemical reactions that metabolize carbon dioxide without the complex proteins used by living organisms today.read more
View ArticleScripps Research Professor Benjamin Cravatt awarded 2022 Wolf Prize in Chemistry
Cravatt awarded prestigious prize for breakthroughs in understanding the role of proteins in biological processes and diseases.read more
View ArticleScripps Research discovery could enable broad coronavirus vaccine
Scientists identified vulnerable site on multiple coronaviruses that could be targeted to prevent future pandemics.read more
View ArticleScientists reveal how Venus flytraps snap shut
LA JOLLA, CA— Scientists at Scripps Research have revealed the three-dimensional structure of Flycatcher1, an aptly named protein channel that may enable Venus flytrap plants to snap shut in response...
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